STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ghrBBifunctional glyoxylate/hydroxypyruvate reductase B; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily. (324 aa)    
Predicted Functional Partners:
AOP79044.1
Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.885
AOP78331.1
Bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.859
AOP76297.1
2-dehydro-3-deoxygluconokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.805
AOP77843.1
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
     
 0.778
AOP78657.1
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
     
 0.778
garR
2-hydroxy-3-oxopropionate reductase; Catalyzes the reduction of tatronate semialdehyde to D- glycerate; Belongs to the HIBADH-related family. 2-hydroxy-3- oxopropionate reductase subfamily.
 
  
 0.755
AOP76296.1
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.746
AOP76342.1
Malate synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family.
   
 
 0.734
AOP76343.1
Isocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.721
ghrA
Bifunctional glyoxylate/hydroxypyruvate reductase A; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
 
  
 
0.716
Your Current Organism:
Enterobacter hormaechei steigerwaltii
NCBI taxonomy Id: 299766
Other names: CIP 108489, DSM 16691, E. hormaechei subsp. steigerwaltii, Enterobacter hormaechei subsp. steigerwaltii, Enterobacter hormaechei subsp. steigerwaltii Hoffmann et al. 2016, Enterobacter sp. GN02457, accession AJ543908, accession AJ853890, strain EN-562
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