STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rcsAHelix-turn-helix transcriptional regulator; Component of the Rcs signaling system, which controls transcription of numerous genes. Binds to DNA to regulate expression of genes. (207 aa)    
Predicted Functional Partners:
barA
Two-component sensor histidine kinase BarA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.998
AOP79806.1
Aerobic respiration two-component sensor histidine kinase ArcB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.970
AOP76412.1
Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.780
rcsC
Two-component system sensor histidine kinase/response regulator; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
  
 0.765
AOP77673.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.744
AOP78937.1
Chemotaxis protein CheV; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.732
rcsD
Phosphotransferase RcsD; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
   
 0.686
rcsB
DNA-binding response regulator; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
     
 0.657
AOP76387.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.586
AOP79695.1
Aerotaxis receptor Aer; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.541
Your Current Organism:
Enterobacter hormaechei steigerwaltii
NCBI taxonomy Id: 299766
Other names: CIP 108489, DSM 16691, E. hormaechei subsp. steigerwaltii, Enterobacter hormaechei subsp. steigerwaltii, Enterobacter hormaechei subsp. steigerwaltii Hoffmann et al. 2016, Enterobacter sp. GN02457, accession AJ543908, accession AJ853890, strain EN-562
Server load: low (16%) [HD]