node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AOP77772.1 | fdx | BFV68_09035 | BFV68_16255 | Fe-S cluster assembly scaffold SufA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. | Ferredoxin, 2Fe-2S type, ISC system; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.884 |
AOP77772.1 | hscA | BFV68_09035 | BFV68_16260 | Fe-S cluster assembly scaffold SufA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU. | 0.628 |
AOP77772.1 | hscB | BFV68_09035 | BFV68_16265 | Fe-S cluster assembly scaffold SufA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. | Co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.926 |
AOP77772.1 | iscR | BFV68_09035 | BFV68_16285 | Fe-S cluster assembly scaffold SufA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. | Fe-S cluster assembly transcriptional regulator IscR; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | 0.793 |
AOP77772.1 | iscS | BFV68_09035 | BFV68_16280 | Fe-S cluster assembly scaffold SufA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. | IscS subfamily cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.937 |
AOP77772.1 | iscU | BFV68_09035 | BFV68_16275 | Fe-S cluster assembly scaffold SufA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. | Fe-S cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.919 |
AOP77772.1 | nfuA | BFV68_09035 | BFV68_20890 | Fe-S cluster assembly scaffold SufA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. | Fe-S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.724 |
AOP79245.1 | iscR | BFV68_16960 | BFV68_16285 | Flagellar motor switch protein FliG; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. | Fe-S cluster assembly transcriptional regulator IscR; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | 0.751 |
fdx | AOP77772.1 | BFV68_16255 | BFV68_09035 | Ferredoxin, 2Fe-2S type, ISC system; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S cluster assembly scaffold SufA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. | 0.884 |
fdx | hscA | BFV68_16255 | BFV68_16260 | Ferredoxin, 2Fe-2S type, ISC system; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU. | 0.990 |
fdx | hscB | BFV68_16255 | BFV68_16265 | Ferredoxin, 2Fe-2S type, ISC system; Derived by automated computational analysis using gene prediction method: Protein Homology. | Co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.996 |
fdx | iscA | BFV68_16255 | BFV68_16270 | Ferredoxin, 2Fe-2S type, ISC system; Derived by automated computational analysis using gene prediction method: Protein Homology. | Iron-sulfur cluster assembly protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB. | 0.984 |
fdx | iscR | BFV68_16255 | BFV68_16285 | Ferredoxin, 2Fe-2S type, ISC system; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S cluster assembly transcriptional regulator IscR; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | 0.710 |
fdx | iscS | BFV68_16255 | BFV68_16280 | Ferredoxin, 2Fe-2S type, ISC system; Derived by automated computational analysis using gene prediction method: Protein Homology. | IscS subfamily cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.996 |
fdx | iscU | BFV68_16255 | BFV68_16275 | Ferredoxin, 2Fe-2S type, ISC system; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.997 |
fdx | nfuA | BFV68_16255 | BFV68_20890 | Ferredoxin, 2Fe-2S type, ISC system; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.666 |
fliG | iscR | BFV68_13650 | BFV68_16285 | Flagellar motor switch protein FliG; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. | Fe-S cluster assembly transcriptional regulator IscR; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | 0.751 |
hscA | AOP77772.1 | BFV68_16260 | BFV68_09035 | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU. | Fe-S cluster assembly scaffold SufA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. | 0.628 |
hscA | fdx | BFV68_16260 | BFV68_16255 | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU. | Ferredoxin, 2Fe-2S type, ISC system; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.990 |
hscA | hscB | BFV68_16260 | BFV68_16265 | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU. | Co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.999 |