STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOP79336.1Transcriptional regulator; Regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa)    
Predicted Functional Partners:
hycE
Hydrogenase 3 large subunit; Formate hydrogenlyase subunit 5; HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.966
AOP79335.1
Formate hydrogenlyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.945
hycD
Hydrogenase 3 membrane subunit; Formate hydrogenlyase subunit 4; HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.771
AOP79331.1
Electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.770
AOP79334.1
Formate hydrogenlyase subunit 3; Catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3); Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.720
AOP79329.1
Required for the maturation of the formate hydrogenlyase complex; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.717
AOP79330.1
Formate hydrogenlyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.714
AOP79328.1
Hydrogenase maturation peptidase HycI; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.705
hypA
Hydrogenase maturation nickel metallochaperone HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
  
 0.590
AOP79342.1
Transcriptional regulator FhlA; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.570
Your Current Organism:
Enterobacter hormaechei steigerwaltii
NCBI taxonomy Id: 299766
Other names: CIP 108489, DSM 16691, E. hormaechei subsp. steigerwaltii, Enterobacter hormaechei subsp. steigerwaltii, Enterobacter hormaechei subsp. steigerwaltii Hoffmann et al. 2016, Enterobacter sp. GN02457, accession AJ543908, accession AJ853890, strain EN-562
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.