STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rutAUnannotated protein; Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate. (363 aa)    
Predicted Functional Partners:
rutB
Unannotated protein; In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2; Belongs to the isochorismatase family. RutB subfamily.
 
  
 0.957
GCA_900068845_03820
Unannotated protein.
 
  
 0.932
rutC
Unannotated protein; May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation.
 
  
 0.910
GCA_900068845_03819
Unannotated protein.
 
  
 0.851
GCA_900068845_03824
Unannotated protein.
 
   
 0.704
rutG
Unannotated protein.
 
  
 0.677
GCA_900068845_00290
Unannotated protein.
 
   
 0.589
GCA_900068845_00292
Unannotated protein.
   
 
 0.575
GCA_900068845_02733
Unannotated protein.
   
 
 0.575
GCA_900068845_03779
Unannotated protein.
 
 
 0.574
Your Current Organism:
Enterobacter ludwigii
NCBI taxonomy Id: 299767
Other names: CCUG 51323, CCUG 51354, CIP 108491, DSM 16688, E. ludwigii, Enterobacter ludwigii Hoffmann et al. 2005, Enterobacter sp. GN02226, Enterobacter sp. GN02730, Pantoea sp. RCE-5, bacterium K9, strain EN-119
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.