STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GCA_900068845_04582Unannotated protein. (432 aa)    
Predicted Functional Partners:
hisC
Unannotated protein; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
 0.966
hisB
Unannotated protein; In the N-terminal section; belongs to the histidinol- phosphatase family.
  
 0.946
hisI
Unannotated protein; In the N-terminal section; belongs to the PRA-CH family.
  
 0.892
hisF
Unannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
 0.883
hisH
Unannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
 0.879
hisG
Unannotated protein; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
  
 0.868
GCA_900068845_04583
Unannotated protein.
 
     0.866
hisA
Unannotated protein.
  
 0.840
GCA_900068845_04584
Unannotated protein.
 
     0.661
GCA_900068845_04585
Unannotated protein.
 
   
 0.616
Your Current Organism:
Enterobacter ludwigii
NCBI taxonomy Id: 299767
Other names: CCUG 51323, CCUG 51354, CIP 108491, DSM 16688, E. ludwigii, Enterobacter ludwigii Hoffmann et al. 2005, Enterobacter sp. GN02226, Enterobacter sp. GN02730, Pantoea sp. RCE-5, bacterium K9, strain EN-119
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.