STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dbus_chrXg634E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (613 aa)    
Predicted Functional Partners:
Dbus_chrXg1370
CG3226.
    
 0.973
Dbus_chr2Lg645
Morgue.
    
 0.888
Dbus_chrXg1308
Arm.
    
  0.772
Dbus_chrXg1307
Arm.
    
  0.772
Dbus_chr2Lg601
Ebi.
    
  0.770
Dbus_chr2Lg602
Rbbp5.
    
  0.770
Dbus_chr2Rg745
Phyl.
    
 0.671
Dbus_chr3Lg259
Uev1A.
    
   0.666
Dbus_chr3Lg273
Ubiquitin carboxyl-terminal hydrolase.
    
  0.588
A0A0M4EM54
CG7215.
     
 0.459
Your Current Organism:
Drosophila busckii
NCBI taxonomy Id: 30019
Other names: D. busckii
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