STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yaeQConserved hypothetical protein; Code: S; COG: COG4681; orf. (181 aa)    
Predicted Functional Partners:
lepB
Signal peptidase I; Code: U; COG: COG0681; Belongs to the peptidase S26 family.
   
    0.882
yaeJ
Conserved hypothetical protein; Code: J; COG: COG1186; orf.
 
     0.838
cspC
Cold shock protein; Code: K; COG: COG1278.
  
    0.804
parC
DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
    0.799
minE
Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
   
    0.764
SDY_1338
Hypothetical protein.
   
    0.764
cutF
Copper homeostasis protein; Lipoprotein; Code: MP; COG: COG3015.
       0.741
SDY_1970
Conserved hypothetical protein.
   
    0.648
rne
RNase E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.
   
    0.602
yfiA
Putative yhbH sigma 54 modulator; Code: J; COG: COG1544.
   
    0.602
Your Current Organism:
Shigella dysenteriae
NCBI taxonomy Id: 300267
Other names: S. dysenteriae Sd197, Shigella dysenteriae Sd197, Shigella dysenteriae str. Sd197, Shigella dysenteriae strain Sd197
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.