STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
marAMarA; Multiple antibiotic resistance; transcriptional activator of defense systems; Code: K; COG: COG2207. (129 aa)    
Predicted Functional Partners:
marR
MarR; Multiple antibiotic resistance protein; repressor of mar operon; Code: K; COG: COG1846.
  
  
 0.989
rhaR
Positive regulator for rhaRS operon; Activates expression of the rhaSR operon in response to L- rhamnose.
  
 
 0.783
rhaS
Positive regulator for rhaBAD operon; Activates expression of the rhaBAD and rhaT operons.
  
 
 0.765
acrR
acrAB operon repressor; Code: K; COG: COG1309.
  
   
 0.753
tolC
Outer membrane channel; Specific tolerance to colicin E1; segregation of daughter chromosomes; Code: MU; COG: COG1538.
      
 0.686
yijO
Putative ARAC-type regulatory protein; Code: K; COG: COG2207.
  
     0.675
ompF
Outer membrane protein 1a (Ia;b;F); Code: M; COG: COG3203; Belongs to the Gram-negative porin family.
      
 0.638
rpoA
RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.614
SDY_3705
Putative transcriptional regulator; Code: K; COG: COG2207.
  
     0.545
emrR
Regulator of plasmid mcrB operon; Microcin B17 synthesis; Code: K; COG: COG1846.
   
  
 0.529
Your Current Organism:
Shigella dysenteriae
NCBI taxonomy Id: 300267
Other names: S. dysenteriae Sd197, Shigella dysenteriae Sd197, Shigella dysenteriae str. Sd197, Shigella dysenteriae strain Sd197
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.