STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDY_1867Putative membrane protein; Code: V; COG: COG1566; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (299 aa)    
Predicted Functional Partners:
SDY_1868
Hypothetical protein.
  
 0.974
SDY_1869
Conserved hypothetical protein; Code: S; COG: COG1289; orf.
  
 0.904
SDY_1866
Conserved hypothetical protein.
  
  
 0.892
ybjZ
Putative ATP-binding component of a transport system; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.783
slyA
Transcriptional regulator for cryptic hemolysin; Transcription regulator that can specifically activate or repress expression of target genes; Belongs to the SlyA family.
 
  
 0.599
emrY
Multidrug resistance protein Y; Code: GEPR; COG: COG0477; Belongs to the major facilitator superfamily.
  
 
 0.564
fhuA
Outer membrane protein receptor for ferrichrome, colicin M, and phages T1, T5, and phi80; Code: P; COG: COG1629.
  
   
 0.545
SDY_1374
Putative outer membrane channel protein; Code: MU; COG: COG1538.
 
 
 0.493
yohG
Putative channel/filament proteins; Code: MU; COG: COG1538.
 
 
 0.478
yhhS
Putative transport; Code: GEPR; COG: COG0477.
  
   0.471
Your Current Organism:
Shigella dysenteriae
NCBI taxonomy Id: 300267
Other names: S. dysenteriae Sd197, Shigella dysenteriae Sd197, Shigella dysenteriae str. Sd197, Shigella dysenteriae strain Sd197
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