lpp protein (Shigella dysenteriae) - STRING interaction network

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Score

lpp

Murein lipoprotein; Code: M; COG: COG4238. (78 aa)

Predicted Functional Partners:

lolA

0.937

tonB

0.915

ycfU

0.861

ycfW

0.793

ompA

0.751

ycfV

0.624

pal

0.535

ompC

0.486

cutC

0.445

insB-65

0.442

Your Current Organism:

Shigella dysenteriae

NCBI taxonomy Id: 300267
Other names: S. dysenteriae Sd197, Shigella dysenteriae Sd197, Shigella dysenteriae str. Sd197, Shigella dysenteriae strain Sd197

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cutC	lpp	SDY_1178	SDY_1908	Copper homeostasis protein; Participates in the control of copper homeostasis.	Murein lipoprotein; Code: M; COG: COG4238.	0.445
insB-65	lpp	SDY_1907	SDY_1908	IS1 ORF2.	Murein lipoprotein; Code: M; COG: COG4238.	0.442
lolA	lpp	SDY_2370	SDY_1908	Periplasmic protein effects translocation of lipoproteins from inner membrane to outer; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	Murein lipoprotein; Code: M; COG: COG4238.	0.937
lolA	ompA	SDY_2370	SDY_0930	Periplasmic protein effects translocation of lipoproteins from inner membrane to outer; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	Outer membrane protein 3a; II*;G;d; Code: M; COG: COG2885; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.	0.567
lolA	ompC	SDY_2370	SDY_0861	Periplasmic protein effects translocation of lipoproteins from inner membrane to outer; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	Outer membrane protein 1b; Ib;c; Code: M; COG: COG3203; Belongs to the Gram-negative porin family.	0.711
lolA	pal	SDY_2370	SDY_0689	Periplasmic protein effects translocation of lipoproteins from inner membrane to outer; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.	0.867
lolA	ycfU	SDY_2370	SDY_2034	Periplasmic protein effects translocation of lipoproteins from inner membrane to outer; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	Conserved hypothetical protein; Code: M; COG: COG4591; orf.	0.970
lolA	ycfV	SDY_2370	SDY_2033	Periplasmic protein effects translocation of lipoproteins from inner membrane to outer; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	Putative ATP-binding component of a transport system; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.	0.955
lolA	ycfW	SDY_2370	SDY_2032	Periplasmic protein effects translocation of lipoproteins from inner membrane to outer; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	Putative kinase; Code: M; COG: COG4591.	0.946
lpp	cutC	SDY_1908	SDY_1178	Murein lipoprotein; Code: M; COG: COG4238.	Copper homeostasis protein; Participates in the control of copper homeostasis.	0.445
lpp	insB-65	SDY_1908	SDY_1907	Murein lipoprotein; Code: M; COG: COG4238.	IS1 ORF2.	0.442
lpp	lolA	SDY_1908	SDY_2370	Murein lipoprotein; Code: M; COG: COG4238.	Periplasmic protein effects translocation of lipoproteins from inner membrane to outer; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	0.937
lpp	ompA	SDY_1908	SDY_0930	Murein lipoprotein; Code: M; COG: COG4238.	Outer membrane protein 3a; II*;G;d; Code: M; COG: COG2885; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.	0.751
lpp	ompC	SDY_1908	SDY_0861	Murein lipoprotein; Code: M; COG: COG4238.	Outer membrane protein 1b; Ib;c; Code: M; COG: COG3203; Belongs to the Gram-negative porin family.	0.486
lpp	pal	SDY_1908	SDY_0689	Murein lipoprotein; Code: M; COG: COG4238.	Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.	0.535
lpp	tonB	SDY_1908	SDY_1316	Murein lipoprotein; Code: M; COG: COG4238.	TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.	0.915
lpp	ycfU	SDY_1908	SDY_2034	Murein lipoprotein; Code: M; COG: COG4238.	Conserved hypothetical protein; Code: M; COG: COG4591; orf.	0.861
lpp	ycfV	SDY_1908	SDY_2033	Murein lipoprotein; Code: M; COG: COG4238.	Putative ATP-binding component of a transport system; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.	0.624
lpp	ycfW	SDY_1908	SDY_2032	Murein lipoprotein; Code: M; COG: COG4238.	Putative kinase; Code: M; COG: COG4591.	0.793
ompA	lolA	SDY_0930	SDY_2370	Outer membrane protein 3a; II*;G;d; Code: M; COG: COG2885; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.	Periplasmic protein effects translocation of lipoproteins from inner membrane to outer; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	0.567