STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fruAPTS system, fructose-specific transport protein; Code: G; COG: COG1299. (563 aa)    
Predicted Functional Partners:
pfkB
6-phosphofructokinase II; Suppressor of pfkA; Code: G; COG: COG1105; Belongs to the carbohydrate kinase PfkB family.
  
 0.999
fruK
Fructose-1-phosphate kinase; Code: G; COG: COG1105; Belongs to the carbohydrate kinase PfkB family.
 
 0.999
fruB
PTS system, fructose-specific IIA/fpr component; Code: G; COG: COG4668.
 
 0.999
ptsH
PTS system protein HPr; Code: G; COG: COG1925.
  
 
 0.985
ptsA
PEP-protein phosphotransferase system enzyme I; Code: G; COG: COG1080; Belongs to the PEP-utilizing enzyme family.
 
  
 0.962
fba
Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.938
SDY_4132
Putative aldolase; Code: G; COG: COG0191.
  
 
 0.938
yajF
Possible NAGC-like transcriptional regulator; Code: KG; COG: COG1940.
    
 0.928
ydjJ
Putative oxidoreductase; Code: ER; COG: COG1063.
   
 
  0.900
SDY_2270
Conserved hypothetical protein; Code: G; COG: COG1830; orf.
     
  0.900
Your Current Organism:
Shigella dysenteriae
NCBI taxonomy Id: 300267
Other names: S. dysenteriae Sd197, Shigella dysenteriae Sd197, Shigella dysenteriae str. Sd197, Shigella dysenteriae strain Sd197
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