STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
emrAMultidrug resistance secretion protein; Code: V; COG: COG1566. (390 aa)    
Predicted Functional Partners:
emrY
Multidrug resistance protein Y; Code: GEPR; COG: COG0477; Belongs to the major facilitator superfamily.
 
 0.962
acrA
Acridine efflux pump; Code: M; COG: COG0845; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  
 0.844
emrR
Regulator of plasmid mcrB operon; Microcin B17 synthesis; Code: K; COG: COG1846.
 
  
 0.844
ybjZ
Putative ATP-binding component of a transport system; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.801
yegB
Putative transport protein; Code: GEPR; COG: COG0477.
 
 
 0.769
yieO
Putative transport protein; Code: GEPR; COG: COG0477; Belongs to the major facilitator superfamily.
 
 0.767
yohG
Putative channel/filament proteins; Code: MU; COG: COG1538.
 
 0.759
tolC
Outer membrane channel; Specific tolerance to colicin E1; segregation of daughter chromosomes; Code: MU; COG: COG1538.
  
 
 0.703
SDY_1374
Putative outer membrane channel protein; Code: MU; COG: COG1538.
 
 
 0.675
SDY_1373
Hypothetical protein.
 
 
 0.650
Your Current Organism:
Shigella dysenteriae
NCBI taxonomy Id: 300267
Other names: S. dysenteriae Sd197, Shigella dysenteriae Sd197, Shigella dysenteriae str. Sd197, Shigella dysenteriae strain Sd197
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