STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ygiBConserved hypothetical protein; Code: S; COG: COG5463; orf; Belongs to the UPF0441 family. (234 aa)    
Predicted Functional Partners:
ygiC
Putative synthetase/amidase; Code: E; COG: COG0754.
 
  
 0.958
yjfC
Putative synthetase/amidase; Code: E; COG: COG0754.
 
  
 0.821
nlpB
Lipoprotein-34; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
     0.649
yifM
Uncharacterized conserved protein; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family.
  
     0.610
yajG
Putative polymerase/proteinase; Code: M; COG: COG3056.
  
     0.599
gsp
Glutathionylspermidine synthetase/amidase; Code: E; COG: COG0754.
 
  
 0.543
wzxE
Putative cytochrome; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family.
  
     0.535
pspB
Phage shock protein.
  
     0.531
tolC
Outer membrane channel; Specific tolerance to colicin E1; segregation of daughter chromosomes; Code: MU; COG: COG1538.
  
    0.520
yciS
Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.
  
     0.518
Your Current Organism:
Shigella dysenteriae
NCBI taxonomy Id: 300267
Other names: S. dysenteriae Sd197, Shigella dysenteriae Sd197, Shigella dysenteriae str. Sd197, Shigella dysenteriae strain Sd197
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