STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yqiBPutative enzyme; Code: S; COG: COG3151. (140 aa)    
Predicted Functional Partners:
yqiE
Conserved hypothetical protein; Code: LR; COG: COG0494; orf.
 
    0.976
icc
Regulator of lacZ; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
 
  
 0.928
yqiA
Conserved hypothetical protein; Code: R; COG: COG3150; orf.
 
     0.781
yohC
Conserved hypothetical protein.
  
     0.642
parE
DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
       0.631
yjaE
Putative transcriptional regulator; Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
  
     0.630
ygfY
Conserved hypothetical protein; Code: S; COG: COG2938; orf.
  
     0.621
yigA
Conserved hypothetical protein; Code: S; COG: COG3159; orf.
  
     0.619
SDY_1262
Conserved hypothetical protein; Code: S; COG: COG3094; orf.
  
     0.579
ygiM
Conserved hypothetical protein; Code: T; COG: COG3103; orf.
  
    0.566
Your Current Organism:
Shigella dysenteriae
NCBI taxonomy Id: 300267
Other names: S. dysenteriae Sd197, Shigella dysenteriae Sd197, Shigella dysenteriae str. Sd197, Shigella dysenteriae strain Sd197
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