STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yqiAConserved hypothetical protein; Code: R; COG: COG3150; orf. (193 aa)    
Predicted Functional Partners:
icc
Regulator of lacZ; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
 
  
 0.956
yqiB
Putative enzyme; Code: S; COG: COG3151.
 
     0.781
tolC
Outer membrane channel; Specific tolerance to colicin E1; segregation of daughter chromosomes; Code: MU; COG: COG1538.
 
     0.748
yqiE
Conserved hypothetical protein; Code: LR; COG: COG0494; orf.
     
 0.720
parE
DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
  
    0.698
helD
DNA helicase IV; Code: L; COG: COG0210.
 
     0.579
msbB
Suppressor of htrB; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A.
 
     0.566
dsbA
Protein disulfide isomerase I; Essential for cytochrome c synthesis and formate-dependent reduction; Code: OC; COG: COG0526.
  
     0.532
sdhD
Succinate dehydrogenase, hydrophobic subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
  
     0.476
ompC
Outer membrane protein 1b; Ib;c; Code: M; COG: COG3203; Belongs to the Gram-negative porin family.
  
     0.471
Your Current Organism:
Shigella dysenteriae
NCBI taxonomy Id: 300267
Other names: S. dysenteriae Sd197, Shigella dysenteriae Sd197, Shigella dysenteriae str. Sd197, Shigella dysenteriae strain Sd197
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.