STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glpRRepressor of the glp operon; Code: KG; COG: COG1349. (252 aa)    
Predicted Functional Partners:
glpG
Protein of glp regulon; Rhomboid-type serine protease that catalyzes intramembrane proteolysis.
      0.855
glpD
Sn-glycerol-3-phosphate dehydrogenase (aerobic); Code: C; COG: COG0578; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.646
glpE
Protein of glp regulon; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
       0.606
gst
Glutathionine S-transferase; Code: O; COG: COG0625.
      
 0.588
rph
RNase PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
      
 0.586
ugpE
Sn-glycerol 3-phosphate transport protein, integral membrane protein; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.
 
   
 0.470
fruK
Fructose-1-phosphate kinase; Code: G; COG: COG1105; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.461
ugpA
Sn-glycerol 3-phosphate transport system, integral membrane protein; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.
 
   
 0.451
pfkB
6-phosphofructokinase II; Suppressor of pfkA; Code: G; COG: COG1105; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.444
fpr
ferredoxin-NADP reductase; Code: C; COG: COG1018.
  
   
 0.433
Your Current Organism:
Shigella dysenteriae
NCBI taxonomy Id: 300267
Other names: S. dysenteriae Sd197, Shigella dysenteriae Sd197, Shigella dysenteriae str. Sd197, Shigella dysenteriae strain Sd197
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