STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hydGSensor HydH response regulator of hydrogenase 3 activity; Code: T; COG: COG2204. (441 aa)    
Predicted Functional Partners:
hydH
Sensor kinase for HydG hydrogenase 3 activity; Code: T; COG: COG0642.
 0.996
rpoN
RNA polymerase, sigma(54 or 60) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.801
SDY_1249
Hypothetical protein.
  
     0.742
SDY_4127
Putative histidine kinase; Code: T; COG: COG0642.
 
 
 0.718
glnL
Histidine protein kinase sensor for GlnG regulator; Nitrogen regulator II, NRII; Code: T; COG: COG3852.
 
 0.702
barA
Sensor-regulator; Activates OmpR by phophorylation; Code: T; COG: COG0642.
 
 
0.630
arcB
Aerobic respiration sensor-response protein; Histidine protein kinase/phosphatase, sensor for arcA; Code: T; COG: COG0642.
 
 
 0.616
ycbO
Conserved hypothetical protein; Code: P; COG: COG0715; orf.
 
  
 0.582
yjaI
Conserved hypothetical protein; Binds zinc. Could be an important component of the zinc- balancing mechanism; Belongs to the ZraP family.
     
 0.582
evgS
Putative sensor for regulator EvgA; Code: ET; COG: COG0834.
  
 
0.566
Your Current Organism:
Shigella dysenteriae
NCBI taxonomy Id: 300267
Other names: S. dysenteriae Sd197, Shigella dysenteriae Sd197, Shigella dysenteriae str. Sd197, Shigella dysenteriae strain Sd197
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