STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phnMPhosphonate metabolism; Code: P; COG: COG3454. (350 aa)    
Predicted Functional Partners:
phnL
ATP-binding component of phosphonate transport; Code: P; COG: COG4778.
 
 
 0.999
phnH
Phosphonate metabolism; Code: P; COG: COG3625.
 
 
 0.998
phnI
Phosphonate metabolism; Code: P; COG: COG3626.
 
 
 0.998
phnJ
Phosphonate metabolism; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose. Belongs to the PhnJ family.
 
 
 0.998
phnK
ATP-binding component of phosphonate transport; Code: P; COG: COG4107.
 
  
 0.989
phnN
ATP-binding component of phosphonate transport; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).
  
 0.988
phnP
Phosphonate metabolism; Code: R; COG: COG1235.
 
  
 0.933
phnF
Putative transcriptional regulator; Code: K; COG: COG2188.
 
  
 0.880
phnD
Periplasmic binding protein component of Pn transporter; Code: P; COG: COG3221.
 
  
 0.857
phnC
ATP-binding component of phosphonate transport; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
 
  
 0.854
Your Current Organism:
Shigella dysenteriae
NCBI taxonomy Id: 300267
Other names: S. dysenteriae Sd197, Shigella dysenteriae Sd197, Shigella dysenteriae str. Sd197, Shigella dysenteriae strain Sd197
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