STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dcuBAnaerobic dicarboxylate transport; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. (395 aa)    
Predicted Functional Partners:
fumB
Fumarase B; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
 0.818
dctA
Uptake of C4-dicarboxylic acids; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
   
  
 0.807
srlR
Regulator for gut (srl) operon; Code: KG; COG: COG1349.
   
  
 0.647
ycaO
Conserved hypothetical protein; Code: S; COG: COG1944; orf.
      
 0.580
aspA
Aspartate ammonia-lyase; Aspartase; Code: E; COG: COG1027.
 
  
 0.552
frdA
Fumarate reductase, anaerobic, flavoprotein subunit; Code: C; COG: COG1053.
 
  
 0.551
yidE
Putative transport protein; Code: R; COG: COG2985.
  
     0.521
insB-123
IS1 ORF2; Code: L; COG: COG1662.
       0.490
ansB
Periplasmic L-asparaginase II; Code: EJ; COG: COG0252; Belongs to the asparaginase 1 family.
 
  
 0.444
yfbV
Conserved hypothetical protein; Code: S; COG: COG3092; orf.
      
 0.439
Your Current Organism:
Shigella dysenteriae
NCBI taxonomy Id: 300267
Other names: S. dysenteriae Sd197, Shigella dysenteriae Sd197, Shigella dysenteriae str. Sd197, Shigella dysenteriae strain Sd197
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