STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
chpBProbable growth inhibitor, PemK-like, autoregulated; Code: T; COG: COG2337. (116 aa)    
Predicted Functional Partners:
chpS
Suppressor of inhibitory function of ChpB, PemI-like, autoregulated; Code: T; COG: COG2336.
 
 0.999
chpR
PemI-like suppressor of inhibitory function of ChpA; Autoregulated; Code: T; COG: COG2336.
 
 
 0.916
yafQ
Conserved hypothetical protein; Code: S; COG: COG3041; orf.
 
   
 0.821
dinJ
Damage-inducible protein J; Code: L; COG: COG3077.
 
   
 0.789
yhhG
Conserved hypothetical protein; Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel.
  
 
 0.666
relB
RelB protein; Code: L; COG: COG3077.
     
 0.659
SDY_2416
Hypothetical protein.
  
   
 0.581
SDY_1736
Conserved hypothetical protein; Code: S; COG: COG1598; orf.
  
   
 0.557
ygjM
Conserved hypothetical protein; Code: K; COG: COG5499; orf.
  
  
 0.529
parE
DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
      
 0.521
Your Current Organism:
Shigella dysenteriae
NCBI taxonomy Id: 300267
Other names: S. dysenteriae Sd197, Shigella dysenteriae Sd197, Shigella dysenteriae str. Sd197, Shigella dysenteriae strain Sd197
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.