STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A182Y7C4Uncharacterized protein. (433 aa)    
Predicted Functional Partners:
A0A182YI94
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.983
A0A182YLC4
RING-type domain-containing protein.
    
 0.978
A0A182Y5X5
Skp1_POZ domain-containing protein; Belongs to the SKP1 family.
    
 0.977
A0A182XVI7
Ubiquitin-like domain-containing protein.
    
 0.976
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
 
 0.923
A0A182Y227
Uncharacterized protein.
   
   0.873
A0A182XYT5
WD_REPEATS_REGION domain-containing protein.
   
 
 0.862
A0A182YNB6
DNA helicase; Belongs to the MCM family.
   
 
 0.832
A0A182YIW9
Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
    
 
 0.797
A0A182XWV7
Uncharacterized protein.
   
 
 0.790
Your Current Organism:
Anopheles stephensi
NCBI taxonomy Id: 30069
Other names: A. stephensi, Anopheles mysorensis, Anopheles stephensi mysorensis, Anopheles stephensi var. mysorensis, Asian malaria mosquito
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.