STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B4135_0114Ribosomal RNA small subunit methyltransferase C. (226 aa)    
Predicted Functional Partners:
rplL
Hypothetical protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.
  
  
 0.873
rplJ
Hypothetical protein; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
    0.766
rplA
Hypothetical protein; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
  
    0.725
B4135_3347
Hypothetical protein; Sporulation initiation phosphotransferase B.
   
    0.657
B4135_2162
Hypothetical protein; Fe-S oxidoreductase.
   
 
 0.635
obg
Hypothetical protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
   
    0.622
rpoB
DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
    0.579
nusG
Hypothetical protein; Participates in transcription elongation, termination and antitermination.
  
  
 0.551
nusA
Hypothetical protein; Participates in both transcription termination and antitermination.
  
    0.531
rplK
Hypothetical protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
  
    0.503
Your Current Organism:
Caldibacillus debilis
NCBI taxonomy Id: 301148
Other names: C. debilis, Caldibacillus debilis (Banat et al. 2004) Coorevits et al. 2012, DSM 16016, Geobacillus debilis, Geobacillus debilis Banat et al. 2004, LMG 23386, LMG:23386, NCIMB 13995, strain R-35653, strain Tf
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