STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiIHypothetical protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (403 aa)    
Predicted Functional Partners:
B4135_1800
Cysteine desulfurase.
 0.959
B4135_3818
Hypothetical protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
   
    0.924
B4135_1516
Cysteine desulfurase.
 
 0.820
B4135_3309
Cysteine desulfurase.
 
 0.795
B4135_1812
Hypothetical protein.
    
 0.718
B4135_1064
Hypothetical protein; tRNA and rRNA cytosine-C5-methylases.
  
    0.629
ezrA
Hypothetical protein; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
       0.584
B4135_4019
Hypothetical protein.
  
  
  0.562
mnmA
Hypothetical protein; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
 
 
 0.531
mnmA-2
Hypothetical protein; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
 
 
 0.528
Your Current Organism:
Caldibacillus debilis
NCBI taxonomy Id: 301148
Other names: C. debilis, Caldibacillus debilis (Banat et al. 2004) Coorevits et al. 2012, DSM 16016, Geobacillus debilis, Geobacillus debilis Banat et al. 2004, LMG 23386, LMG:23386, NCIMB 13995, strain R-35653, strain Tf
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