STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B4135_2663Hypothetical protein; 4-hydroxybenzoyl-CoA thioesterase family active site. (140 aa)    
Predicted Functional Partners:
B4135_2298
Enoyl-CoA hydratase [isoleucine degradation] / 3-hydroxyacyl-CoA dehydrogenase.
  
 
 0.808
B4135_3790
Malonyl CoA-acyl carrier protein transacylase.
  
 0.798
acpP
Hypothetical protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 0.672
B4135_2662
Hypothetical protein.
       0.572
fabH
3-oxoacyl-[acyl-carrier-protein] synthase, KASIII; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
   
 0.568
fabZ
Hypothetical protein; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
    
 0.567
fabF
3-oxoacyl-[acyl-carrier-protein] synthase, KASII; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
    
 0.555
B4135_2578
Acyl-CoA hydrolase.
  
 
 0.542
B4135_2664
Dihydrodipicolinate synthase.
       0.537
B4135_3724
Hypothetical protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
    
   0.514
Your Current Organism:
Caldibacillus debilis
NCBI taxonomy Id: 301148
Other names: C. debilis, Caldibacillus debilis (Banat et al. 2004) Coorevits et al. 2012, DSM 16016, Geobacillus debilis, Geobacillus debilis Banat et al. 2004, LMG 23386, LMG:23386, NCIMB 13995, strain R-35653, strain Tf
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