node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
apt | gmk | GCA_900166595_02005 | GCA_900166595_02538 | Unannotated protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Unannotated protein; Essential for recycling GMP and indirectly, cGMP. | 0.953 |
apt | guaA | GCA_900166595_02005 | GCA_900166595_00878 | Unannotated protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Unannotated protein; Catalyzes the synthesis of GMP from XMP. | 0.987 |
apt | guaB | GCA_900166595_02005 | GCA_900166595_00317 | Unannotated protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Unannotated protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.525 |
apt | guaC | GCA_900166595_02005 | GCA_900166595_00241 | Unannotated protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Unannotated protein; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.926 |
apt | hpt | GCA_900166595_02005 | GCA_900166595_00060 | Unannotated protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Unannotated protein; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.926 |
apt | purA | GCA_900166595_02005 | GCA_900166595_00280 | Unannotated protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Unannotated protein; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.444 |
apt | purH | GCA_900166595_02005 | GCA_900166595_00979 | Unannotated protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Unannotated protein. | 0.949 |
apt | surE | GCA_900166595_02005 | GCA_900166595_04003 | Unannotated protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Unannotated protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.911 |
apt | xpt | GCA_900166595_02005 | GCA_900166595_01401 | Unannotated protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Unannotated protein; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.913 |
apt | yhcR | GCA_900166595_02005 | GCA_900166595_03591 | Unannotated protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Unannotated protein. | 0.931 |
gmk | apt | GCA_900166595_02538 | GCA_900166595_02005 | Unannotated protein; Essential for recycling GMP and indirectly, cGMP. | Unannotated protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.953 |
gmk | guaA | GCA_900166595_02538 | GCA_900166595_00878 | Unannotated protein; Essential for recycling GMP and indirectly, cGMP. | Unannotated protein; Catalyzes the synthesis of GMP from XMP. | 0.967 |
gmk | guaB | GCA_900166595_02538 | GCA_900166595_00317 | Unannotated protein; Essential for recycling GMP and indirectly, cGMP. | Unannotated protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.555 |
gmk | guaC | GCA_900166595_02538 | GCA_900166595_00241 | Unannotated protein; Essential for recycling GMP and indirectly, cGMP. | Unannotated protein; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.919 |
gmk | hpt | GCA_900166595_02538 | GCA_900166595_00060 | Unannotated protein; Essential for recycling GMP and indirectly, cGMP. | Unannotated protein; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.923 |
gmk | purA | GCA_900166595_02538 | GCA_900166595_00280 | Unannotated protein; Essential for recycling GMP and indirectly, cGMP. | Unannotated protein; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.400 |
gmk | surE | GCA_900166595_02538 | GCA_900166595_04003 | Unannotated protein; Essential for recycling GMP and indirectly, cGMP. | Unannotated protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
gmk | xpt | GCA_900166595_02538 | GCA_900166595_01401 | Unannotated protein; Essential for recycling GMP and indirectly, cGMP. | Unannotated protein; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.955 |
gmk | yhcR | GCA_900166595_02538 | GCA_900166595_03591 | Unannotated protein; Essential for recycling GMP and indirectly, cGMP. | Unannotated protein. | 0.912 |
guaA | apt | GCA_900166595_00878 | GCA_900166595_02005 | Unannotated protein; Catalyzes the synthesis of GMP from XMP. | Unannotated protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.987 |