prkg2 protein (Pundamilia nyererei) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

prkg2

cGMP-dependent protein kinase. (773 aa)

Predicted Functional Partners:

gucy1b1

0.903

GUCY1A2

0.903

LOC102209105

0.903

ENSPNYP00000011447

0.881

ENSPNYP00000011458

0.881

LOC102198676

0.872

LOC102196768

0.837

pla2g4a

0.831

creb5

0.826

akap10

0.809

Your Current Organism:

Pundamilia nyererei

NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPNYP00000011447	GUCY1A2	ENSPNYP00000011447	ENSPNYP00000019875	Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.822
ENSPNYP00000011447	LOC102209105	ENSPNYP00000011447	ENSPNYP00000024175	Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.981
ENSPNYP00000011447	gucy1b1	ENSPNYP00000011447	ENSPNYP00000011422	Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.983
ENSPNYP00000011447	prkg2	ENSPNYP00000011447	ENSPNYP00000008182	Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	cGMP-dependent protein kinase.	0.881
ENSPNYP00000011458	LOC102209105	ENSPNYP00000011458	ENSPNYP00000024175	Uncharacterized protein.	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.981
ENSPNYP00000011458	gucy1b1	ENSPNYP00000011458	ENSPNYP00000011422	Uncharacterized protein.	Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.982
ENSPNYP00000011458	prkg2	ENSPNYP00000011458	ENSPNYP00000008182	Uncharacterized protein.	cGMP-dependent protein kinase.	0.881
GUCY1A2	ENSPNYP00000011447	ENSPNYP00000019875	ENSPNYP00000011447	Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.822
GUCY1A2	LOC102209105	ENSPNYP00000019875	ENSPNYP00000024175	Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.983
GUCY1A2	gucy1b1	ENSPNYP00000019875	ENSPNYP00000011422	Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.986
GUCY1A2	prkg2	ENSPNYP00000019875	ENSPNYP00000008182	Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	cGMP-dependent protein kinase.	0.903
LOC102196768	prkg2	ENSPNYP00000000612	ENSPNYP00000008182	Regulator of G protein signaling 2.	cGMP-dependent protein kinase.	0.837
LOC102198676	prkg2	ENSPNYP00000023644	ENSPNYP00000008182	Malate synthase-like.	cGMP-dependent protein kinase.	0.872
LOC102209105	ENSPNYP00000011447	ENSPNYP00000024175	ENSPNYP00000011447	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.981
LOC102209105	ENSPNYP00000011458	ENSPNYP00000024175	ENSPNYP00000011458	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Uncharacterized protein.	0.981
LOC102209105	GUCY1A2	ENSPNYP00000024175	ENSPNYP00000019875	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.983
LOC102209105	gucy1b1	ENSPNYP00000024175	ENSPNYP00000011422	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.839
LOC102209105	prkg2	ENSPNYP00000024175	ENSPNYP00000008182	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	cGMP-dependent protein kinase.	0.903
akap10	prkg2	ENSPNYP00000030574	ENSPNYP00000008182	A kinase (PRKA) anchor protein 10.	cGMP-dependent protein kinase.	0.809
creb5	prkg2	ENSPNYP00000019727	ENSPNYP00000008182	Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription.	cGMP-dependent protein kinase.	0.826