STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ubr4Ubiquitin protein ligase E3 component n-recognin 4. (4863 aa)    
Predicted Functional Partners:
LOC102213483
Uncharacterized protein.
    
 
 0.909
kcmf1
Potassium channel modulatory factor 1.
    
 
 0.909
huwe1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.
   
 
 0.784
trip12
Thyroid hormone receptor interactor 12.
   
 
 0.716
CALML6
Calmodulin like 6.
    
 
 0.646
uba5
Ubiquitin-like modifier activating enzyme 5.
   
 
 0.644
atg7
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]
   
 
 0.644
LOC102207027
Ubiquitin-like modifier activating enzyme 3.
   
 
 0.638
UBA3
E2_bind domain-containing protein.
   
 
 0.638
hectd1
HECT domain containing 1.
   
  
 0.618
Your Current Organism:
Pundamilia nyererei
NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei
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