STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPIDRScaffold protein involved in DNA repair. (935 aa)    
Predicted Functional Partners:
LOC102203240
BLM RecQ like helicase.
    
 0.714
top3a
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
   
  0.711
rmi2
RecQ mediated genome instability 2.
    
  0.702
rmi1
RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae).
    
  0.702
ENSPNYP00000003197
SWIM-type zinc finger 7 associated protein 1.
    
 
 0.699
ENSPNYP00000011819
RecQ helicase-like 4.
    
 0.694
top3b
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
   
  0.684
tdrd3
Tudor domain containing 3.
    
  0.681
recql5
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
    
 0.609
UNC79
Unc-79 homolog, NALCN channel complex subunit.
      
 0.597
Your Current Organism:
Pundamilia nyererei
NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.