STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPNYP00000032004Uncharacterized protein. (423 aa)    
Predicted Functional Partners:
ENSPNYP00000024874
Helicase ATP-binding domain-containing protein.
    
 0.958
ENSPNYP00000024941
ERCC4 domain-containing protein.
    
 0.958
h6pd
Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase).
   
 
 0.814
lin52
Lin-52 DREAM MuvB core complex component.
    
 0.671
lin54
Lin-54 DREAM MuvB core complex component.
    
 0.668
ENSPNYP00000012893
Lin-9 DREAM MuvB core complex component.
    
 0.663
LOC102215177
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 0.653
RPA1
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 0.653
ENSPNYP00000012090
FA complementation group C.
    
  0.604
fancg
FA complementation group G.
    
  0.604
Your Current Organism:
Pundamilia nyererei
NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.