STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (215 aa)    
Predicted Functional Partners:
JF72_10070
DNA polymerase III, delta subunit.
 
 
 0.977
tdk
Thymidine kinase.
  
 
 0.973
recR
Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
    
 0.960
dut
DUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
  
 
 0.954
JF72_12030
Deoxycytidylate deaminase.
    
 0.944
JF72_10120
Uncharacterized protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
 
    0.931
rsmI
Ribosomal RNA small subunit methyltransferase I; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
 
    0.904
JF72_10060
Initiation-control protein YabA; Involved in initiation control of chromosome replication. Belongs to the YabA family.
  
    0.894
JF72_10080
Uncharacterized protein.
 
    0.884
dnaX
DNA polymerase III; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
  
 0.860
Your Current Organism:
Lactobacillus apis
NCBI taxonomy Id: 303541
Other names: CCM 8403, L. apis, LMG 26964, LMG:26964, Lactobacillus apis Killer et al. 2014, Lactobacillus sp. ESL0185, Lactobacillus sp. R4B, Lactobacillus sp. R4C, strain R4B
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.