node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C662_01390 | C662_15406 | C662_01390 | C662_15406 | COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | 0.577 |
C662_01390 | C662_18428 | C662_01390 | C662_18428 | COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Type 11 methyltransferase; COG0500 SAM-dependent methyltransferases. | 0.602 |
C662_01390 | bioB | C662_01390 | C662_01405 | COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.996 |
C662_01390 | bioC | C662_01390 | C662_11992 | COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Type 11 methyltransferase; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.525 |
C662_01390 | bioC-2 | C662_01390 | C662_15583 | COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthesis protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.541 |
C662_01390 | bioD | C662_01390 | C662_01400 | COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.999 |
C662_01390 | bioF | C662_01390 | C662_01395 | COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.998 |
C662_01390 | ubiE | C662_01390 | C662_04418 | COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.458 |
C662_15406 | C662_01390 | C662_15406 | C662_01390 | COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.577 |
C662_15406 | C662_18428 | C662_15406 | C662_18428 | COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | Type 11 methyltransferase; COG0500 SAM-dependent methyltransferases. | 0.415 |
C662_15406 | bioB | C662_15406 | C662_01405 | COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.954 |
C662_15406 | bioD | C662_15406 | C662_01400 | COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.590 |
C662_15406 | bioF | C662_15406 | C662_01395 | COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.873 |
C662_18428 | C662_01390 | C662_18428 | C662_01390 | Type 11 methyltransferase; COG0500 SAM-dependent methyltransferases. | COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.602 |
C662_18428 | C662_15406 | C662_18428 | C662_15406 | Type 11 methyltransferase; COG0500 SAM-dependent methyltransferases. | COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | 0.415 |
C662_18428 | bioB | C662_18428 | C662_01405 | Type 11 methyltransferase; COG0500 SAM-dependent methyltransferases. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.634 |
C662_18428 | bioD | C662_18428 | C662_01400 | Type 11 methyltransferase; COG0500 SAM-dependent methyltransferases. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.594 |
C662_18428 | bioF | C662_18428 | C662_01395 | Type 11 methyltransferase; COG0500 SAM-dependent methyltransferases. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.605 |
C662_19399 | bioB | C662_19399 | C662_01405 | COG1509 Lysine 2,3-aminomutase. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.629 |
bioB | C662_01390 | C662_01405 | C662_01390 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.996 |