STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C662_02980Excisionase DNA binding domain-containing protein; COG3311 Predicted transcriptional regulator. (104 aa)    
Predicted Functional Partners:
C662_14481
COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
     
 0.937
C662_05175
COG0067 Glutamate synthase domain 1.
    
  0.911
icmF
methylmalonyl-CoA mutase, large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
     
 0.771
C662_16748
COG0281 Malic enzyme.
     
 0.720
C662_17683
COG0281 Malic enzyme.
     
 0.720
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
     
 0.619
C662_03355
COG0372 Citrate synthase; Belongs to the citrate synthase family.
    
 0.542
C662_05655
Rhs element Vgr protein; COG3501 Uncharacterized protein conserved in bacteria.
   
    0.533
C662_10671
COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits.
     
 0.431
C662_16120
COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits.
     
 0.431
Your Current Organism:
Thauera sp. 28
NCBI taxonomy Id: 303682
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.