STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C662_03633COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (540 aa)    
Predicted Functional Partners:
C662_15593
Hypothetical protein; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
 0.927
C662_00300
Formate dehydrogenase subunit beta; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit.
    
 
 0.848
C662_11468
Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit.
    
 
 0.848
C662_03818
COG2124 Cytochrome P450.
  
 0.834
C662_03613
3-hydroxyacyl-CoA dehydrogenase; COG1024 Enoyl-CoA hydratase/carnithine racemase.
 
 0.798
rplF
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.780
C662_14481
COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
    
 0.773
rplM
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
    
 
 0.717
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
   
   0.717
rplO
50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
    
   0.717
Your Current Organism:
Thauera sp. 28
NCBI taxonomy Id: 303682
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.