STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C662_06107Histidine kinase; COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation. (707 aa)    
Predicted Functional Partners:
C662_06102
Two component sigma-54 specific Fis family transcriptional regulator; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.
 
 0.972
C662_06112
Hypothetical protein.
 
    0.956
C662_08699
Putative sensor-regulator protein; COG0642 Signal transduction histidine kinase.
 
 
0.955
C662_09800
COG0642 Signal transduction histidine kinase.
 
 
0.943
C662_11735
Hpt domain-containing protein; COG2198 FOG: HPt domain.
   
 0.939
C662_18918
COG0642 Signal transduction histidine kinase.
 
 
0.937
C662_15553
Hypothetical protein; COG2202 FOG: PAS/PAC domain.
   
 0.934
C662_17898
Hpt sensor hybrid histidine kinase; COG0642 Signal transduction histidine kinase.
 
 
0.914
C662_08360
Response regulator receiver; COG2199 FOG: GGDEF domain.
  
 0.883
C662_17878
Diguanylate cyclase/phosphodiesterase; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.
  
 0.883
Your Current Organism:
Thauera sp. 28
NCBI taxonomy Id: 303682
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