Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
C662_08060Hypothetical protein; Belongs to the UPF0229 family. (426 aa)    
Predicted Functional Partners:
C662_08065
SpoVR family protein.
 
  
 0.995
C662_08055
PrkA family serine protein kinase; COG2766 Putative Ser protein kinase.
 
  
 0.992
nnrE
Carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]
       0.596
napD
Periplasmic nitrate reductase subunit NapD; Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin- arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
   
    0.535
C662_16240
Hypothetical protein.
   
    0.526
C662_08150
PhoH family protein; COG1875 Predicted ATPase related to phosphate starvation-inducible protein PhoH.
   
    0.524
C662_10676
Glu/Leu/Phe/Val dehydrogenase dimerization region; COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
    0.514
C662_16235
Hypothetical protein.
   
    0.514
C662_09870
COG0656 Aldo/keto reductases, related to diketogulonate reductase.
   
    0.500
C662_08075
COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family.
       0.445
Your Current Organism:
Thauera sp. 28
NCBI taxonomy Id: 303682
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