Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
C662_08080Hypothetical protein; COG0133 Tryptophan synthase beta chain. (190 aa)    
Predicted Functional Partners:
C662_15051
COG2916 DNA-binding protein H-NS.
  
     0.692
C662_08075
COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family.
       0.664
C662_12427
Branched-chain amino acid ABC transporter.
 
     0.612
C662_03478
COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
  
     0.599
C662_14666
HNS-like transcription regulator protein; COG2916 DNA-binding protein H-NS.
  
     0.552
C662_02640
Molybdopterin binding domain-containing protein; COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA.
  
     0.512
nnrE
Carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]
       0.496
C662_12942
Phasin family protein.
  
     0.433
Your Current Organism:
Thauera sp. 28
NCBI taxonomy Id: 303682
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