Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
C662_08085COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (317 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 
 0.614
C662_03310
COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.601
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
 
 0.600
C662_08090
Extradiol ring-cleavage dioxygenase III subunit B.
       0.555
C662_08095
COG3038 Cytochrome B561.
       0.544
C662_08100
Hypothetical protein; Belongs to the UPF0312 family.
       0.544
C662_08789
COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.509
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.496
C662_05175
COG0067 Glutamate synthase domain 1.
     
 0.479
C662_18358
COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.417
Your Current Organism:
Thauera sp. 28
NCBI taxonomy Id: 303682
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