STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C662_09835COG0294 Dihydropteroate synthase and related enzymes. (276 aa)    
Predicted Functional Partners:
C662_00605
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.
 
 0.999
C662_00995
FolC bifunctional protein; COG0285 Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.
 
 0.998
C662_00140
COG1539 Dihydroneopterin aldolase.
  
 
 0.977
C662_02590
COG1539 Dihydroneopterin aldolase.
  
 
 0.977
C662_00275
COG0147 Anthranilate/para-aminobenzoate synthases component I.
 
 
 0.976
folE
COG0302 GTP cyclohydrolase I.
 
 
 0.953
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
  
  
 0.900
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
  
 0.770
ftsH
ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
  
 0.724
C662_10631
COG0512 Anthranilate/para-aminobenzoate synthases component II.
 
  
 0.668
Your Current Organism:
Thauera sp. 28
NCBI taxonomy Id: 303682
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.