STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C662_13291Protease Do; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Belongs to the peptidase S1C family. (483 aa)    
Predicted Functional Partners:
C662_13306
Anti sigma-E protein, RseA; COG3073 Negative regulator of sigma E activity.
  
 
 0.928
C662_18368
Protease Do; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Belongs to the peptidase S1C family.
  
  
 
0.900
C662_13296
Positive regulator of sigma E, RseC/MucC.
  
  
 0.837
C662_13286
Thioredoxin-disulfide reductase; COG0526 Thiol-disulfide isomerase and thioredoxins.
  
   0.810
C662_08919
Peptidase S1 and S6 chymotrypsin/Hap; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.
  
  
  0.773
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
   
 0.763
C662_13276
COG0681 Signal peptidase I; Belongs to the peptidase S26 family.
 
   
 0.721
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
     
 0.702
era
GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
   
 
 0.665
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
  
   0.653
Your Current Organism:
Thauera sp. 28
NCBI taxonomy Id: 303682
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