Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
C662_175432-hydroxy-3-oxopropionate reductase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases. (295 aa)    
Predicted Functional Partners:
C662_17538
2-hydroxy-3-oxopropionate reductase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.
 
  
 
0.954
C662_01990
COG3622 Hydroxypyruvate isomerase; Belongs to the hyi family.
 
 0.904
C662_14481
COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
    
  0.867
C662_01985
COG3960 Glyoxylate carboligase; Belongs to the TPP enzyme family.
 
 
 0.815
C662_14236
D-isomer specific 2-hydroxyacid dehydrogenase; COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.802
C662_12152
CoA-binding protein; COG1042 Acyl-CoA synthetase (NDP forming).
    
  0.641
C662_13181
CoA-binding protein; COG1042 Acyl-CoA synthetase (NDP forming).
    
  0.641
C662_16275
FAD linked oxidase; COG0277 FAD/FMN-containing dehydrogenases.
    
 0.626
C662_05380
Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; COG2030 Acyl dehydratase.
     
 0.610
C662_06452
COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.576
Your Current Organism:
Thauera sp. 28
NCBI taxonomy Id: 303682
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