STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N306_13743Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (147 aa)    
Predicted Functional Partners:
N306_07032
Very-long-chain enoyl-CoA reductase.
   
 0.930
N306_15150
Estradiol 17-beta-dehydrogenase 12.
   
 0.912
N306_12874
Trans-2,3-enoyl-CoA reductase-like.
   
 0.896
N306_14397
Hydroxysteroid dehydrogenase-like 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.868
N306_00977
Elongation of very long chain fatty acids protein.
     
 0.813
N306_14145
Glutathione S-transferase kappa 1.
    
 0.781
N306_10628
Elongation of very long chain fatty acids protein.
    
 0.775
N306_02162
Elongation of very long chain fatty acids protein.
    
 0.775
ELOVL5
Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...]
    
 0.775
N306_14452
Elongation of very long chain fatty acids protein.
    
 0.774
Your Current Organism:
Opisthocomus hoazin
NCBI taxonomy Id: 30419
Other names: O. hoazin, Opisthocomus hoazin hoazin, hoatzin
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