STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N306_14250Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (120 aa)    
Predicted Functional Partners:
N306_02458
Histone H2A deubiquitinase MYSM1.
    
 0.995
N306_08008
Histone H3.2.
 
 
 0.963
N306_04056
Histone acetyltransferase type B catalytic subunit.
    
 0.935
N306_00812
Histone H3.
 
 
 0.934
N306_02876
Histone H2A; Belongs to the histone H2A family.
 
 
 0.933
N306_07897
Histone acetyltransferase KAT2B.
    
 0.914
N306_03943
AT-rich interactive domain-containing protein 4A.
    
 0.912
N306_12472
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
    
 0.885
N306_12242
Retinoblastoma-binding protein 5.
    
 0.883
N306_03660
Ubiquitin-40S ribosomal protein S27a.
   
 0.881
Your Current Organism:
Opisthocomus hoazin
NCBI taxonomy Id: 30419
Other names: O. hoazin, Opisthocomus hoazin hoazin, hoatzin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.