node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
N306_00259 | N306_03059 | A0A091VKA6 | A0A091VJW1 | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. | cAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. | 0.948 |
N306_00259 | N306_03477 | A0A091VKA6 | A0A091WAX7 | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. | 0.986 |
N306_00259 | N306_05915 | A0A091VKA6 | A0A091WSY6 | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. | Calcium-transporting ATPase type 2C member 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. | 0.874 |
N306_00259 | N306_07497 | A0A091VKA6 | A0A091WCX4 | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. | Calcium-transporting ATPase type 2C member 1; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. | 0.874 |
N306_00259 | N306_08985 | A0A091VKA6 | A0A091WB41 | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.796 |
N306_00259 | N306_10032 | A0A091VKA6 | A0A091WHR4 | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. | cAMP-dependent protein kinase catalytic subunit PRKX. | 0.892 |
N306_00259 | N306_12320 | A0A091VKA6 | A0A091W793 | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. | cGMP-dependent protein kinase 1. | 0.840 |
N306_00259 | N306_13210 | A0A091VKA6 | A0A091XIK5 | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. | Plasma membrane calcium-transporting ATPase 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. | 0.796 |
N306_03059 | N306_00259 | A0A091VJW1 | A0A091VKA6 | cAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. | 0.948 |
N306_03059 | N306_08985 | A0A091VJW1 | A0A091WB41 | cAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.856 |
N306_03059 | N306_12320 | A0A091VJW1 | A0A091W793 | cAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. | cGMP-dependent protein kinase 1. | 0.914 |
N306_03059 | N306_13210 | A0A091VJW1 | A0A091XIK5 | cAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. | Plasma membrane calcium-transporting ATPase 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. | 0.857 |
N306_03477 | N306_00259 | A0A091WAX7 | A0A091VKA6 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. | 0.986 |
N306_03477 | N306_04200 | A0A091WAX7 | A0A091XIW9 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. | Na_Ca_ex domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. | 0.489 |
N306_03477 | N306_08985 | A0A091WAX7 | A0A091WB41 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.747 |
N306_03477 | N306_11887 | A0A091WAX7 | A0A091VBP1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. | Cell cycle control protein 50A. | 0.633 |
N306_03477 | N306_13210 | A0A091WAX7 | A0A091XIK5 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. | Plasma membrane calcium-transporting ATPase 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. | 0.746 |
N306_04200 | N306_03477 | A0A091XIW9 | A0A091WAX7 | Na_Ca_ex domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. | 0.489 |
N306_04200 | N306_05915 | A0A091XIW9 | A0A091WSY6 | Na_Ca_ex domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. | Calcium-transporting ATPase type 2C member 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. | 0.489 |
N306_04200 | N306_07497 | A0A091XIW9 | A0A091WCX4 | Na_Ca_ex domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. | Calcium-transporting ATPase type 2C member 1; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. | 0.489 |