Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MCP_0064Putative ATP-dependent helicase. (824 aa)    
Predicted Functional Partners:
MCP_0066
Putative transcriptional regulator.
 
     0.704
MCP_2322
Conserved hypothetical protein; Contains one RNA binding S1 domain (IPR003029); Contains one RNucleic acid binding, OB-fold, tRNA/helicase-type domain (IPR004365).; Contains one Phosphoesterase, RecJ-like (IPR001667).
 
    0.683
aroK
Shikimate kinase.
 
     0.681
MCP_0063
Conserved hypothetical protein.
       0.671
rps8e
30S ribosomal protein S8e.
 
     0.671
tyrS
tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
 
     0.634
MCP_2845
Conserved hypothetical protein; Belongs to the Protein of unknown function UPF0153 family (IPR005358).
 
    0.624
rpoA1
DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
   
 0.617
mutS2
Putative DNA mismatch repair protein; Has ATPase and non-specific DNA-binding activities. Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily.
  
     0.616
rpoB2
DNA-directed RNA polymerase subunit B''; Belongs to the RNA polymerase beta chain family.
  
   
 0.613
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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