STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ligT2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. (181 aa)    
Predicted Functional Partners:
cca
CCA-adding enzyme; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
 
     0.828
MCP_2831
Conserved hypothetical protein; Contains one Adenylate/cytidine kinase, N-terminal domain (IPR011769); Belongs to the Protein of unknown function DUF54 family (IPR002739).
       0.714
MCP_0080
Conserved hypothetical protein; Contains at least two 4Fe-4S ferredoxin, iron-sulfur binding domains (IPR001450).
  
    0.654
MCP_0081
Family X DNA polymerase.
       0.641
MCP_0079
Conserved hypothetical protein; Contains one Protein of unknown function DUF362 domain (IPR007160).
       0.640
MCP_1656
Molybdopterin binding, CinA-related family protein; Contains one Molybdopterin binding domain (IPR001453).
     
 0.474
MCP_0078
Conserved hypothetical protein.
       0.470
rtcB
Conserved hypothetical protein; Belongs to the Protein of unknown function UPF0027 family (IPR001233).
 
   
 0.455
trpS
tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp).
     
 0.405
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.