STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccaCCA-adding enzyme; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (443 aa)    
Predicted Functional Partners:
ligT
2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.
 
     0.828
MCP_1909
ThiF/MoeB sulfur transfer protein.
  
 
 0.825
MCP_2342
Conserved hypothetical protein; Contains one UBA/THIF-type NAD/FAD binding fold domain (IPR000594).
  
 
 0.825
MCP_2831
Conserved hypothetical protein; Contains one Adenylate/cytidine kinase, N-terminal domain (IPR011769); Belongs to the Protein of unknown function DUF54 family (IPR002739).
 
     0.780
endA
tRNA-splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
 
   
 0.724
MCP_0080
Conserved hypothetical protein; Contains at least two 4Fe-4S ferredoxin, iron-sulfur binding domains (IPR001450).
  
    0.666
spt5
Putative ribosomal protein L26e; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
  
     0.665
MCP_0725
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF655 family (IPR007003).
 
   
 0.654
nac
Nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
 
     0.644
MCP_0079
Conserved hypothetical protein; Contains one Protein of unknown function DUF362 domain (IPR007160).
       0.636
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.