Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCP_0106Conserved hypothetical protein; Contains one AMMECR1 domain (IPR002733). (206 aa)    
Predicted Functional Partners:
MCP_1640
Conserved hypothetical protein; Contains one Protein of unknown function DUF52 domain (IPR002737); Belongs to the MEMO1 family.
    0.990
MCP_0624
Conserved hypothetical protein; Contains one Radical SAM domain (IPR007197).
     0.980
MCP_1516
Archaeosine tRNA-ribosyltransferase.
       0.582
pgk-1
Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
       0.581
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
       0.536
MCP_0291
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF373 family (IPR007254).
       0.536
MCP_1091
Putative endonuclease IV.
       0.536
MCP_0045
GTP-binding protein.
       0.504
MCP_1494
Conserved hypothetical protein.
    
   0.490
MCP_1449
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF82 family (IPR002782).
       0.466
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
Server load: low (16%) [HD]