STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCP_0137Conserved hypothetical protein; Belongs to the Protein of unknown function DUF460 family (IPR007408). (658 aa)    
Predicted Functional Partners:
tfe
Transcription initiation factor E; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation comple [...]
  
   
 0.671
cdc6-2
Cell division control protein 6 homolog; Involved in regulation of DNA replication.
  
     0.611
MCP_2705
Putative oligosaccharyl transferase.
  
     0.605
MCP_2246
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF106, transmembrane family (IPR002809).
  
     0.582
MCP_2814
Putative ArsR family transcriptional regulator.
  
     0.577
MCP_0190
Conserved hypothetical protein; Belongs to the Protein of unknown function DUF63 family (IPR002749).
  
     0.570
MCP_0724
Putative DNA-directed RNA polymerase subunit F.
  
     0.570
MCP_1253
AAA ATPase; Belongs to the AAA ATPase family.
 
     0.552
MCP_2990
Single-stranded DNA-binding replication protein.
 
     0.548
MCP_2849
Putative single-stranded DNA-binding replication protein.
 
     0.547
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.