Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MCP_0178Hypothetical protein; Contains at least one Tetratricopeptide region domain (IPR013026); Contains at least four Tetratricopeptide TPR_1 repeats (IPR001440).; Contains at least three Tetratricopeptide TPR_2 repeats (IPR013105). (373 aa)    
Predicted Functional Partners:
MCP_0179
Conserved hypothetical protein; Contains one Beta-lactamase-like domain (IPR001279).
 
    0.816
MCP_1774
Hypothetical protein; Contains at least one Ankyrin repeatrepeat (IPR002110); Contains at least one PBS lyase HEAT-like repeat (IPR004155).
 
 0.709
MCP_0933
Hypothetical protein; Contains at least one Ankyrin repeat (IPR002110).
 
 0.677
MCP_2662
Hypothetical protein.
 
     0.670
MCP_1229
Hypothetical protein; Contains at least one Tetratricopeptide region domain (IPR013026); Contains at least four Tetratricopeptide TPR_2 repeats (IPR013105).; Contains at least four Tetratricopeptide TPR_1 repeats (IPR001440).
 
    
0.667
dnaK
Heat shock protein 70; Acts as a chaperone.
  
 0.660
ruvB
Holliday junction ATP-dependent DNA helicase RuvB.
  
 0.649
rpoH
DNA-directed RNA polymerase subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.
  
 0.645
rpoD
DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.633
MCP_2698
Protein kinase; Contains at least one Tetratricopeptide region domain (IPR013026); Contains at least three Tetratricopeptide TPR_1 repeats (IPR001440).; Contains at least five Tetratricopeptide TPR_2repeats (IPR013105).
 
 
 
0.632
Your Current Organism:
Methanocella paludicola
NCBI taxonomy Id: 304371
Other names: M. paludicola SANAE, Methanocella paludicola SANAE, methanogenic archaeon SANAE, methanogenic archaeon str. SANAE, methanogenic archaeon strain SANAE
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